Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999
Report date:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD guideline No. 402
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Type of coverage:
semiocclusive
Duration of exposure:
24 h
Doses:
2000mg/kg

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
No deaths occured during the study.
Clinical signs:
No clinical signs and no cutaneous reactions were observed during the study.
Body weight:
The body weight gain of the animals was not influenced by treatment.
Gross pathology:
Marroscopic examiation of the main organs of the animals revealed no apparent abnormalities.

Applicant's summary and conclusion

Conclusions:
Under our experimental conditions, the dermal LD50 of the test substance Pseudo Kharismal Step 1 is higher than 2000 mg/kg in rats. No signs of toxicity were observed at this dose.
Executive summary:

Under our experimental conditions, the dermal LD50 of the test substance Pseudo Kharismal Step 1 is higher than 2000 mg/kg in rats. No signs of toxicity were observed at this dose.