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Physical & Chemical properties

Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 May - 21 May 2018
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
GLP compliance:
Type of method:
flask method
Specific details on test material used for the study:
- Test material: 4-Aminobenzoyl-b-alanine
- Batch number: 12/18
- Purity: NLT 96%
- Storage: Room temperature
Key result
Water solubility:
11.75 g/L
Conc. based on:
test mat.
Incubation duration:
<= 3 d
20 °C
Details on results:
The analytical method proved to be specific, linear, precise and accurate, as follows:
Specificity: It was demonstrated that the blank (mobile phase) did not produce any peak interfering with those of the active ingredient.
Linearity: R: 0.9999; R2: 0.9997; Slope: 45.5143; Intercept: 97.1775; Confidence interval at 95% for the intercept: [-2.5628;2.5628]
Accuracy: Average recovery: 100.69 [95% confidence limits 100.18, 101.19]; RSD: 0.7%
Precision: Assay: 1.172% w/w; RSD%: 0.24
The water solubility of 4-Aminobenzoyl-b-alanine at 20°C was 11.75 g/L.

Description of key information

The water solubility of 4 -Aminobenzoyl-b-alanine at 20°C was determined according to OECD Guideline 105 and was found to be 11.75 g/L.

Key value for chemical safety assessment

Water solubility:
11.75 g/L
at the temperature of:
20 °C

Additional information