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Description of key information

The absorption efficiencies used in the assessment are:
Dermal - 10%
Oral - 100%
Inhalation - 100%

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
Absorption rate - dermal (%):
Absorption rate - inhalation (%):

Additional information

There are no specific toxicokinetic studies of 2 -EHDPP, but toxicology testing appears to indicate that it is readily absorbed via the oral route. Due to its rapid hydrolysis in water, it may be appropriate to consider the toxicokinetics of phenol for oral and inhalation routes since there would be a high likelihood of hydrolysis via these routes. The Phenol RAR (ECB 2006) concludes 100% absorption via the oral and inhalation routes and rapid elimination with low potential for bioaccumulation. These conclusions are also being applied to 2 -EHDPP.

The basis for the dermal absorption recommendation is discussed in Section 7.1.2.