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EC number: 821-184-6 | CAS number: 1777721-60-4
Density
Administrative data
- Endpoint:
- density, other
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 February 2018 - 29 March 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- pycnometer method
Test material
- Reference substance name:
- (2S,3S)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[2.2.2]octane-2-carboxylic acid
- EC Number:
- 821-184-6
- Cas Number:
- 1777721-60-4
- Molecular formula:
- C13H15ClFN3O2
- IUPAC Name:
- (2S,3S)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study reports): JNJ-63757096-AAA (T003689)
- Physical state: solid (powder)
- Appearance: white powder
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: I16ED2695
- Analytical purity: 99.3%
- Expiration date: 28 May 2018
- Storage condition: At room temperature
Results and discussion
Density
- Key result
- Type:
- density
- Density:
- 1.46 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: The difference between the results of the two measurements was < 0.02 g/cm³. According to the guideline, the density of the test item is therefore given as the mean value.
Any other information on results incl. tables
The density (ρ) of a substance is the quotient of its mass and its volume and is expressed in SI units of kg/m³.
The individual measurements were obtained with an accuracy of <0.02 g/cm³.
The individual density measurements were 1.457 g/cm³ (test 1) and 1.457 g/cm³ (test 2).
Applicant's summary and conclusion
- Conclusions:
- The density of the test item at 20ºC was 1.46 g/cm³ (1.46 x 10³ kg/m³).
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