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Physical & Chemical properties

Particle size distribution (Granulometry)

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Administrative data

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December 27th, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Principles of method if other than guideline:
Laser light scattering. The test was performed according to the SOP - STR 071 protocol.
The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measures the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
48.374 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Percentile:
D10
Mean:
1.753 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Percentile:
D90
Mean:
193.05 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Conclusions:
d(0.5): 48.374 µm
Executive summary:

The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measures the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.

Analysis carried out after 2 minutes of ultrasonic treatment:

d(0.1): 1.753 µm

d(0.5): 48.374 µm

d(0.9): 193.050 µm

Conclusion

d(0.1): 1.753 µm

d(0.5): 48.374 µm

d(0.9): 193.050 µm

Description of key information

d(0.5): 48.374 µm

Additional information

Laser light scattering