Registration Dossier
Registration Dossier
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EC number: 601-499-3 | CAS number: 117933-89-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Remarks:
- Acute Toxicity test is performed at sa-FORD, Plot V -10, MIDC Industrial Area, Taloja, Dist Raigad, Navi Mumbai, PIN: 410208, Maharashtra, India
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 44 days
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Version / remarks:
- Karanaorg was found to be "unclassified" or "catagory 5" as per GHS.
- Deviations:
- no
- GLP compliance:
- yes
- Test type:
- acute toxic class method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-(2,4-Dimethylcyclohex-3-ene-1-yl)-5-methyl-(1-methylpropyl)-1,3-dioxane
- EC Number:
- 601-499-3
- Cas Number:
- 117933-89-8
- Molecular formula:
- C17H30O2
- IUPAC Name:
- 2-(2,4-Dimethylcyclohex-3-ene-1-yl)-5-methyl-(1-methylpropyl)-1,3-dioxane
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: feed
- Vehicle:
- corn oil
Results and discussion
- Preliminary study:
- Under the conditions of acute oral toxicity study in female rats: the acute oral LD50 of KARANAORG was found to be greater than 2000 mg/kg body weight and is classified as "catagory 5" or "Unclassified" as per GHS.
Effect levels
- Key result
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 - < 5 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Classified as Catagory 5 as per GHS
Applicant's summary and conclusion
- Conclusions:
- The Acute Oral Toxicity for 2-(2,4-Dimethylcyclohex-3-ene-1-yl)-5-methyl-(1-methylpropyl)-1,3-dioxane is performed as per OECD 423 guideline on Wistar rats . LD 50 for the compound was found to be >2000mg/Kg body weight and is classified as Category 5 / Unclassified as per GHS .
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