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For the aquatic toxicity of the test substance, GLP guideline studies are available for all trophic levels ranging from aquatic microorganisms to fish. No toxic effects towards aquatic freshwater organisms of all four trophic levels (microorganisms, algae, daphnia, and fish) were observed up to the limit of the water solubility of the test substance. Therefore, no PNEC aqua (freshwater) and no PNEC intermittent releases can be derived and a quantitative risk assessment cannot be performed.