Registration Dossier
Registration Dossier
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EC number: 201-145-4 | CAS number: 78-81-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- NOAEC
- 500 mg/m³
- Study duration:
- subchronic
- Species:
- rat
- Quality of whole database:
- 1
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
The NOAEC for systemic toxicity was 500 mg/m3 in the 90-day inhalation toxicity study. Because the Guidance Value Range to assist in potential STOT RE classification (specific target organ toxicity repeated exposure) is 10 - 100 mg/kg/day for the inhalation route of exposure, no classification is justified for the substance according to the CLP Regulation.
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