Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 245-624-6 | CAS number: 23382-12-9
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- The 3 cited publications are on 2-aminoethanol, not 2-aminoethanol hydrobromide.
A read-across approach was indeed performed between 2-aminoethanol hydrobromide (target substance) and 2-aminoethanol (source substance).
QSAR predictions for salt substances such as 2-aminoethanol hydrobromide used to remove the counter ion (or the inorganic part, or the lowest MW part of the salt molecule) and, if necessary, the subsequent neutralization. This procedure is needed to calculate the descriptors used to make the predictions. This read-across approach has been confirmed by several experts, both academic and regulators (European Agency for chemicals, ECHA).
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Environmental fate constantsfor organic chemicals under consideration for EPA's hazardous waste identification projects
- Author:
- Kollig, HP et al.
- Year:
- 1 993
- Bibliographic source:
- EPA/600/R-93/132
- Reference Type:
- review article or handbook
- Title:
- Handbook of property estimation methods for chemicals
- Author:
- Boethling, R., MacKay, D.
- Year:
- 2 000
- Bibliographic source:
- CRC Press, Boca Raton, FL, USA
- Reference Type:
- publication
- Title:
- Rate of hydrolysis
- Author:
- Harris JC
- Year:
- 1 990
- Bibliographic source:
- in: Lyman WJ et al., Handbook of chemical property estimation methods, 3rd edition, ACS Washington.
Materials and methods
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
