Registration Dossier
Registration Dossier
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EC number: 664-492-4 | CAS number: 742087-49-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- Version / remarks:
- Details of the exact method are not given in the CIR text
- GLP compliance:
- not specified
- Remarks:
- results given in the CIR review do not give details of the GLP status of the work carried out
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- D-Glucopyranose, oligomeric, C10-16-alkyl glycosides
- Cas Number:
- 110615-47-9
- Molecular formula:
- C18H36O6
- IUPAC Name:
- D-Glucopyranose, oligomeric, C10-16-alkyl glycosides
Constituent 1
- Specific details on test material used for the study:
- 50% ai (as C10-16 APG; n: 1.6)
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- No. of animals per sex per dose:
- 5
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- None of the animals died during the study
- Clinical signs:
- other: Slight depression, hunched posture, mild to marked erythema, and marked desquamation were observed.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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