Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Description of key information

Based on the results of a dose range finding study it was concluded that a repeated dose study with the undiluted substance is not possible. Taking into account that it was impossible to develop an analytical method it was concluded that it is technically not feasible to dose animals to a stable form of the test item and to conduct a repeated dose study. The considerations are also included in the read across document, attached in Section 13.

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available

Effects on developmental toxicity

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available

Justification for classification or non-classification

In absence of data on reproduction and developmental toxicity due to the fact that testing was found to be technically not feasible, 1,4-H6XDI is not classified for reproduction and developmental toxicity according to the CLP Regulation (EC) No. 1272/2008.

Additional information