Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from peer-reviewed database, acceptable methof of grouping substances by regarding their functional groups
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Reference
Reference Type:
review article or handbook
Title:
Hazardous Substances Database (HSDB)
Author:
HSDB
Year:
2008
Bibliographic source:
U.S. National library of medicine - Toxnet (available online), Search results for N-Methylacetamide, CAS No. 79-16-3. Database content through Dec 2006.

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N-methylacetamide
EC Number:
201-182-6
EC Name:
N-methylacetamide
Cas Number:
79-16-3
Molecular formula:
C3H7NO
IUPAC Name:
N-methylacetamide

Results and discussion

Any other information on results incl. tables


N-Methylacetamide is not expected to undergo hydrolysis in the  
environment due to the slow rate of reaction for amide functional groups 
nor to directly photolyze due to the lack of absorption in the 
environmental UV spectrum (> 290 nm).

Applicant's summary and conclusion