Registration Dossier
Registration Dossier
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EC number: 701-473-2 | CAS number: -
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 442B (Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA)
- GLP compliance:
- yes (incl. QA statement)
- Type of study:
- mouse local lymph node assay (LLNA): BrdU-ELISA
Test material
- Reference substance name:
- Reaction products of olecid acid, 2-(2-aminoethylamino)-ethanol, epichlorhydrin and bisulfit-dimethylsulfat quaternized
- Molecular formula:
- not available for UVCB
- IUPAC Name:
- Reaction products of olecid acid, 2-(2-aminoethylamino)-ethanol, epichlorhydrin and bisulfit-dimethylsulfat quaternized
- Test material form:
- other: paste
Constituent 1
In vivo test system
Test animals
- Species:
- mouse
- Strain:
- CBA:JN
- Sex:
- female
Results and discussion
In vivo (LLNA)
Resultsopen allclose all
- Key result
- Parameter:
- SI
- Variability:
- results not yet available
- Test group / Remarks:
- results not yet available
- Remarks on result:
- other: results not yet available
- Parameter:
- SI
- Variability:
- results not yet available
- Test group / Remarks:
- results not yet available
- Remarks on result:
- other: results not yet available
- Parameter:
- SI
- Variability:
- results not yet available
- Test group / Remarks:
- results not yet available
- Remarks on result:
- other: results not yet available
Applicant's summary and conclusion
- Conclusions:
- The skin sensitisation potential of the test item will be determined.
- Executive summary:
A study will be performed in accordance with OECD TG 442B in order to determine the skin sensitization potential of the test item. The results will be updated as soon as available.The study was initiated before 31 March 2018 but was not completed by the CRO in due time to complete the registration dossier. The
study record will be updated as soon as the results will become available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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