1-Propanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N-methyl-N-[2-[(1-oxo-9-octadecen-1-yl)amino]ethyl]-3-sulfo-, methyl sulfate, sodium salt (1:1:1)

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-04-18 to 2018-04-18

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

31 May 2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

ring method

Key result

Surface tension:

42.51 mN/m

Temp.:

20.2 °C

Conc.:

90 vol%

The instrument was calibrated with 0.3, 0.5, and 0.8 g of standard weights. The surface tensions of standard weights were observed and recorded as 24.40, 40.70, and 65.30 mN/m, respectively. A calibration curve was drawn between the observed surface tension and the standard weights.

The surface tensions of water were observed and recorded as 72.70 and 72.60 mN/m for replicates R1 and R2, respectively. The literature value for the surface tension of water was divided by measured surface tension of water.

Table: Determination of surface tension on test item

Replication Number	Surface Tension of Test item (mN/m) (20.2°C)	Water Calibration Correction Factor	Corrected Surface Tension (mN/m)	Mean of Corrected Surface Tension (mN/m)	SD (±)	RSD (%)
1	42.60	1.0010	42.64	42.51	0.32	0.753
2	42.10	1.0010	42.14
3	42.70	1.0010	42.74
Note: SD - Standard Deviation, RSD – Relative Standard Deviation

SD: Standard Deviation

RSD: Relative Standard Deviation

The test item concentration of 90% of saturation solubility was used for the analysis. Triplicate samples of the test item  were prepared for the analysis and the values obtained are 42.64, 42.14, and 42.74 mN/m for replicates R1, R2 and R3, respectively. The calculated mean surface tension of test item was found to be 42.51 mN/m with RSD of 0.753% at 20.2 ºC.

Conclusions:

The surface tension was determined to be 42.51 mN/m with RSD of 0.753% at 20.2 ºC.

Executive summary:

The surface tension of of the test item was determined according to OECD Guideline 115 (adopted: 27 July 1995) and EU Method A.5 under GLP conditions. The test item of 90% of saturation concentration of the solution was used for the analysis. Triplicate samples of the test item were prepared for the analysis and the values obtained are 42.64, 42.14, and 42.74 mN/m for replicates R1, R2 and R3, respectively. The calculated mean surface tension of the test item was determined to be 42.51 mN/m with RSD of 0.753% at 20.2 ºC.

Description of key information

The surface tension of the substance was determined to be 42.51 mN/m with RSD of 0.753% at 20.2 ºC.

Key value for chemical safety assessment

Surface tension:

42.51

Additional information

The surface tension of the test item was measured under GLP conditions according to OECD Guideline 115 and EU Method A.5. The test item of 90% of saturation concentration of the solution was used for the analysis. Triplicate samples of the test item were prepared for the analysis and the values obtained are 42.64, 42.14, and 42.74 mN/m for replicates R1, R2 and R3, respectively. The calculated mean surface tension of the test item was determined to be 42.51 mN/m with RSD of 0.753% at 20.2 ºC.