Registration Dossier
Registration Dossier
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EC number: 202-809-6 | CAS number: 100-00-5
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Justification for classification or non-classification
Male and female mice showed a significant increase in vascular tumors at the high dose level
(localisation of the vascular tumors was not specified). The
incidences of vascular tumors for male rats at low dose level were 2/14
animals and at high dose level 4/14 animals
(simultaneous control: 0/14, pooled control: 5/99).
In female mice were 2/20 animals at the low dose level and
at high dose level 7/18 animals with vacular tumors
There was evidence of carcinogenicity for male and female mice indicated by increased incidence of vascular tumors.
Classification:
DSD: Category 3, Xn, R40 Limited evidence of a carcinogenic effect
EU-GHS: Category 2 carcinogen
Additional information
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