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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-06-12 to 2017-08-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
15 mg/L
Conc. based on:
test mat.
Incubation duration:
37 d
Temp.:
20 °C
pH:
ca. 5
Details on results:
The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C. The examined pH values are approx. 5 in all sample solutions.

An overview of sampling dates of flask 1, the determined sample content as well as the corresponding deviations are summarised in table 1.

Table 1: Sampling and determined sample content of flask 1

sampling date

test duration [d]

determined sample content [mg/L]

deviation from the previous measurement [%]

2017-07-04

22

15

-

2017-07-05

23

17

+12

2017-07-07

25

17

+3

2017-10-07

28

18

+4

 

mean (n=4)

17

 

SD

1,3

RSD [%]

7,9

Agitation of all flasks was stopped after 37 days as the last three control points differed no more than 15 % and showed no significant upward tendency.

Final examination of flasks 2 to 5 was conducted on 19. Jul. 2017 after 24 hours of temperature equilibration (20 °C ± 0.5 °C). The examined data from TC measurements are given in table 2 together with the weigh-in of each sample and the measured pH values.

Table 2: Final examination of flasks 2 to 5

flask no.

weigh-in [g]

volume (water) [mL]

pH (approx.) [-]

calculated water solubility [mg/L]

2

1,9190

75

5

13

3

1,9270

75

5

14

4

1,9331

75

5

18

5

-

75

5

≤ 1

 

mean (n=6)

15

SD

2,3

RSD [%]

15,1

Conclusions:
The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C and pH 5. The water solubility was determined according to OECD Guideline 105.
Executive summary:

The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C and pH 5. The water solubility was determined according to OECD Guideline 105.

Description of key information

The mean calculated water solubility of the test item Vinylcyclohexane is 15 mg/L at 20 °C ± 0.5 °C and pH 5. The water solubility was determined according to OECD Guideline 105.

Key value for chemical safety assessment

Water solubility:
15 mg/L
at the temperature of:
20 °C

Additional information