Registration Dossier
Registration Dossier
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EC number: 825-518-1 | CAS number: 2060541-47-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No activated sludge respiration inhibition tests are available for Sodium tallowamphopolycarboxy glucinate. The result as observed for the structurally strongly related Sodium oleylamphopolycarboxy glycinate will therefore be used instead. For fish and daphnia identical results were observed for both substances considering their identical structure and properties this read across is considered to be justified.
One activated sludge respiration test with Sodium oleylamphopolycarboxy glycinate is available which was performed in accordance with OECD Test Guideline 209, and in compliance with the OECD principles of Good Laboratory Practice.
The toxicity of sodium oleylamphopolycarboxyglycinate to activated sludge was determined at a contact time of 3 hours, using various concentrations of the test substance. The EC50of sodium oleylamphopolycarboxyglycinate for activated sludge after 3 hours contact time is >1280 mg/L test substance. The EC10 value was 170 mg/L test substance. Sodium oleylamphopolycarboxyglycinate is therefore considered not harmful to activated sludge.
Based on active ingredient (29.8%) the 3h EC50 >381.44 mg/L
Based on active ingredient the 3h EC10 = 50.66 mg/L
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 50.66 mg/L
Additional information
No activated sludge respiration inhibition tests are available for Sodium tallowamphopolycarboxy glucinate. The result as observed for the structurally strongly related Sodium oleylamphopolycarboxy glycinate will therefore be used instead. For fish and daphnia identical results were observed for both substances considering their identical structure and properties this read across is considered to be justified.
One activated sludge respiration test with Sodium oleylamphopolycarboxy glycinate is available.
The toxicity to activated sludge was determined in accordance with OECD Test Guideline 209, and in compliance with the OECD principles of Good Laboratory Practice.
The test is valid as shown by the EC50 of the reference compound 3,5-dichlorophenol (12 mg/L) and the coefficient of variation of the replicates of the control oxygen uptake rates (9%). The average oxygen uptake rate for the control replicates is lower (16 mg O2/g dry weight/hour) than the prescribed rate (>20 mg O2/g dry weight /hour). This does not influence the sensitivity of the activated sludge as shown by comparable EC50 values of the reference substance 3,5-dichlorophenol at oxygen uptake rates lower and higher than the prescribed rate (AkzoNobel 2012). The lower average oxygen uptake rate does therefore not compromise the test outcome in terms of robustness of the endpoints obtained for the test and reference substance and does not invalidate the test.
The toxicity of sodium oleylamphopolycarboxyglycinate to activated sludge was determined at a contact time of 3 hours, using various concentrations of the test substance. The inhibitory effect of sodium oleylamphopolycarboxyglycinate at a particular concentration is expressed as a percentage of the two controls. From the results EC values were calculated. The EC50of sodium oleylamphopolycarboxyglycinate for activated sludge after 3 hours contact time is >1280 mg/L. The EC80 value could not be determined and the EC10 and EC20 values were 170 and 474 mg/L, respectively. Sodium oleylamphopolycarboxyglycinate is therefore considered not harmful to activated sludge.
Based on active ingredient (29.8%) the 3h EC50 >381.44 mg/L
Based on active ingredient the 3h EC10 = 50.66 mg/L
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