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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

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Administrative data

skin sensitisation: in vitro
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)

Data source

Reference Type:
study report

Materials and methods

Test guideline
according to guideline
OECD Guideline 442D (In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method)
GLP compliance:
yes (incl. QA statement)
Type of study:
activation of keratinocytes

Test material

Constituent 1
Test material form:
solid: crystalline
Details on test material:
Batch number 37160906202

Results and discussion

In vitro / in chemico

Remarks on result:
not determinable because of methodological limitations
Other effects / acceptance of results:
Copper (II) dimethyldithiocarbamate was classified as inconclusive according to the KeratinoSens prediction model due to high cytotoxicity

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification