Copper bis(dimethyldithiocarbamate)

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018 72hours

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)

GLP compliance:

yes

Analytical monitoring:

yes

Remarks:

ICP-MS

Vehicle:

no

Test organisms (species):

Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Details on test organisms:

TEST ORGANISM
- Common name: Alga
- Strain: Pseudokirchneriella subcapitata CCAP 278/4 Received 15 May 2018
- Source (laboratory, culture collection): Culture collection of Algae and Protozoa, SMAS Research services Ltd, Scottish marine institute, OBAN Argyll Scotland
- Age of inoculum (at test initiation):
- Method of cultivation: From a pre-culture growing in exponential phase, deionised water with added nutrients according to OECD 201

ACCLIMATION
- Acclimation period:
- Culturing media and conditions (same as test or not):
- Any deformed or abnormal cells observed:

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

72 h

Reference substance (positive control):

no

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 1 - < 10 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat. (total fraction)

Basis for effect:

growth rate

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 0.1 - < 1 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat. (total fraction)

Basis for effect:

other: Yield

Validity criteria fulfilled:

yes

Conclusions:

72 hour EC50 by percent inhibition by yield and percent inhibition by growth rate were both in the range of 1-10mg/L

Executive summary:

72 hour EC50  by percent inhibition by yield and percent inhibition by growth rate were both in the range of 1-10mg/L

Description of key information

EC50 for growth rate at 72 hours is 1.0 -10mg/L