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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02 - 20 December 2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: European Commision, Directorate General XII-JRC, Science Research and Development-Joint Research Centre. "Particle Size Distribution, Fibre Length and Diameter Distribution" Guidance Document, ECB/TM/February 1996
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: European Commission, Directorate General JRC, Joint Research Centre, "Particle Size Distribution, Fibre Length and Diameter Distribution" Draft Guidance Document, EUR 20268 EN (2002), Part 5.2 "Laser scattering / diffraction"
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
sieving
Type of distribution:
mass based distribution
Specific details on test material used for the study:
- Batch n°: 00467090 (charge 05C0836)
- Expiration date: 04 May 2006
- Purity: 99.9%
- Storage condition of test material: at room temperature at about 20°C
No.:
#1
Size:
2 000 µm
Distribution:
0.05 %
Remarks on result:
other: mean of two sievings
No.:
#2
Size:
1 000 µm
Distribution:
4.59 %
Remarks on result:
other: mean of two sievings
No.:
#3
Size:
500 µm
Distribution:
37.8 %
Remarks on result:
other: mean of two sievings
No.:
#4
Size:
250 µm
Distribution:
44.98 %
Remarks on result:
other: mean of two sievings
No.:
#5
Size:
125 µm
Distribution:
12.33 %
Remarks on result:
other: mean of two sievings
No.:
#6
Size:
75 µm
Distribution:
0.26 %
Remarks on result:
other: mean of two sievings
No.:
#7
Size:
< 75 µm
Distribution:
0 %
Remarks on result:
other: mean of two sievings

TIC2782 (T002907) is a white crystalline powder.

The fraction, which passes the 250 μm sieve, is usually used for the measurement using the laser diffraction apparatus. Only about 12.5 % of the test item passed the 250 μm sieve. This amount of test item is insignificant for the evaluation of the particle size distribution.

Conclusions:
T002907 is a white crystalline powder. The particle size distribution of T002907 was determined by the sieving test (following European Commission Guidelines). Only about 12.5% of the test item passed the 125 µm sieve. This amount of the test item is insignificant for the evaluation of the particle size distribution. The results of the study can be considered reliable without restriction.

Description of key information

T002907 is a white crystalline powder. The particle size distribution of T002907 was determined by the sieving test (following European Commission Guidelines). Only about 12.5% of the test item passed the 125 µm sieve. This amount of the test item is insignificant for the evaluation of the particle size distribution.

Additional information