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Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17.10.2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
no
Type of method:
static method

Test material

Constituent 1
Chemical structure
Reference substance name:
(S)-pyrrolidine-2-carboxamide
EC Number:
231-397-0
EC Name:
(S)-pyrrolidine-2-carboxamide
Cas Number:
7531-52-4
Molecular formula:
C5H10N2O
IUPAC Name:
(S)-pyrrolidine-2-carboxamide

Results and discussion

Vapour pressure
Temp.:
25 °C
Vapour pressure:
< 0.111 Pa
Remarks on result:
other: estimated according to modified Grain method
Transition / decomposition
Transition / decomposition:
yes
Transition temp.:
110 °C

Any other information on results incl. tables

The test item was melted at 100 °C. The vapour pressure could not be measured at 110 °C as the pressure continuously increasing due to slow thermal decomposition. After 2 hours at 110 °C the initially clearless melt has turned into yellow. Therefore an established calculation method was used for vapour pressure estimation. 

Applicant's summary and conclusion