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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: screening test, other
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Title:
Unnamed
Year:
2010

Materials and methods

Principles of method if other than guideline:
QSAR predition
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
α-phenylpiperidine-2-acetic acid
EC Number:
243-020-7
EC Name:
α-phenylpiperidine-2-acetic acid
Cas Number:
19395-41-6
Molecular formula:
C13H17NO2
IUPAC Name:
α-phenylpiperidine-2-acetic acid
Test material form:
solid: granular
Specific details on test material used for the study:
C1CCNC(C1)C(C2=CC=CC=C2)C(=O)O

Results and discussion

% Degradation
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
not readily biodegradable
Conclusions:
The prediction is adequate for the Classification and Labelling or risk assessment of the substance as indicated in REACH Regulation (EC) 1907/2006: Annex XI Section 1.3. The predictions do not indicate extreme or acute toxicities relevant for classification and labelling. The assessment indicates that the prediction is suitable for the regulatory conclusion in accordance with the tonnage driven information requirements.