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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 Sep 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
due to the expected very high solubility (miscibility with water) only the preliminary test was performed for confirmation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Remarks:
preliminary test

Test material

Constituent 1
Chemical structure
Reference substance name:
2-[(oxolan-2-yl)methoxy]ethan-1-ol
EC Number:
608-659-1
Cas Number:
31692-85-0
Molecular formula:
C5H10O2[C2H4O]n, n = 0, 1, 2, 3, 4, ... (data given for max n of 4)
IUPAC Name:
2-[(oxolan-2-yl)methoxy]ethan-1-ol
Test material form:
liquid

Results and discussion

Water solubility
Water solubility:
> 3 420 g/L
Remarks on result:
completely miscible
Remarks:
temperature given as "room temperature" (ca. 20 °C), pH not available

Any other information on results incl. tables

The first preliminary tests at room temperature with up to 0.6 mL water showed fume and a lot of bubbles; the test item seemed not to be dissolved. Additional tests with a higher amount of water were carried out, summarized in the table:

Total amount of test item / g

Volume of water / mL

Stirring time / min

Remark

2.7

5

-

dissolved

3.5

5

-

dissolved

4.2

5

-

dissolved

6.4

5

-

dissolved

8.8

5

-

dissolved

12.5

5

-

dissolved

17.1

5

-

dissolved

Thus, it can be estimated that the solubility of the test item in water is > 3420 g/L.

Applicant's summary and conclusion