Registration Dossier
Registration Dossier
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EC number: 251-718-8 | CAS number: 33885-52-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A study was performed to assess the acute toxicity of the substance to Daphnia magna under semi-static conditions (renewal period: 24 hours). The study was conducted in accordance with OECD TG 202 and GLP principles. Groups of twenty daphnids (less than 24 hours old) were exposed for 48 hours to five concentrations of the substance dispersed in test water (4.6 - 100 % of a saturated solution prepared at a loading rate of 100 mg/L) and an untreated control. The incidence of immobilisation was recorded for each test and control group at 24 hours and at 48 hours. After 24 hours at 0.46; 0.99; 2.3 and 5.0 mg/l 5, 30, 100 and 100% immobility, respectively was seen. At 48 hours the immobilisation increased. At these concentrations the immobility was 35, 100, 100 and 100%, respectively. This results in the 48-h EC50 of 0 51 mg/L. All results are expressed in terms of arithmic mean measured concentrations. Measured concentrations ranged from 73 - 89 % of initial at the end of the first renewal period (t=0-24 hours) and 91 -95 % of initial at the end of the second renewal period (t=24-48 hours).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.51 mg/L
Additional information
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