Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
skin sensitisation: in vitro
Data waiving:
study technically not feasible
Justification for data waiving:
Justification for type of information:
According to hydrolysis test results, the hydrolysis rate is estimated to be within several minutes. The hydrolysis products have been identified to be 1-propanol and zirconium dioxide. The sensitsation effect of those organic parts have been well-investigated separately.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

No studies were conducted on the target substance. As the target substance hydrolyses rapidly (half-life < 5 minutes) the intrinsic properties are related to hydrolysis products of the target substance, 1 -propanol.

Animal and human data demonstrate that the substance has no skin sensitizing potential. There is only one report of a woman showing allergic skin reactions after patch testing to propan-1-ol and 2-propanol and other substances. There is no need to classify and label the substance for skin sensitizing properties. There are no data on sensitization by inhalation.

(European Risk Assessment Report, Propan-1 -ol)


Based on these findings, the target substance was considered not skin sensitizing.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

The target substance is not classified as skin sensitizer according to CLP Regulation.