Registration Dossier
Registration Dossier
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EC number: 245-711-9 | CAS number: 23519-77-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- The target substance is hydrolytically unstable with hydrolysis half-life less than 5 minute. The hydrolysis products include 1-propanol and hydrated zirconium dioxide. The ecotoxicity data of the organic parts have been well-investigated and used for read-across.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38412 Part 11, Daphnia- Short term test
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 3 644 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 48h CC50, flow though method, tesed on Daphnia magna was 3644 mg/l for 1-propanol
Referenceopen allclose all
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3 644 mg/L
Additional information
No studies were conducted on the target substance, Zirconium tetrapropanolate. As the target substance hydrolyses rapidly (half-life < 5 minutes) the intrinsic properties are related to hydrolysis products of the target substance.
On the basis that if entering the environmental, this substance will quickly dissociate to form the inorganic (poorly soluble) zirconium dioxide and well-evaluated organic substances – 1-propanol.
The zirconium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.
EC50 (48h) values tested on Daphnia magna were 3644 mg/l for1-propanol (Kuehn, et al. 1989). This value was used for CSA.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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