N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2007-03-19 to 2007-06-20

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

EEC Publication no. L383, December 29, 1992

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

July 27, 1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Decomp. temp.:

>= 150 °C

Remarks on result:

not determinable

Preliminary test

From the start until approximately 150°C the weight of the sample slightly decreased. From approximately 150°C upwards the weight of the sampie significantly decreased. At 234°C, the sampie weight had decreased by 25%. After the experiment, a dark brown coloured (original colour: orange - light brown) residue remained in the sampie pan. The change of the colour of the test substance indicates reaction and/or decomposition.

Main study

During cooling, a glass transition was observed between -10°C and -50°C. During heating, a glass transition was observed between -50°C and -15°C, with an extrapolated onset temperature of -28°C in the first experiment and -29°C in the second experiment. Above approximately 150°C reaction and/or decomposition of the test substance was observed. After the experiment, a sticky, yellowish coloured liquid remained in the sample container.

Besides a glass transition between -50°C (223 K) and -15°C (258 K) with an extrapolated onset of -29°C (244 K), no melting and/or boiling was observed below the temperature of 150°C (423 K) at which reaction and/or decomposition of the test substance started. Therefore, the test substance has no melting and/or boiling temperature.

Conclusions:

No melting point was found.

Executive summary:

The melting point of Amphopropionate C8 was determined according to OECD Guideline 102 (27 July 1995) and EU Method A.1 (29 December 1992) using differential scanning calorimetry.

Besides a glass transition between -50°C (223 K) and -15°C (273 K) with an extrapolated onset of -29°C (244 K), no melting was observed below the temperature of 150°C (423 K) at which reaction and/or decomposition of the test substance started. Therefore, the test substance has no melting temperature.

Description of key information

No melting point was found below decomposition temperature of 150°C (423 K) (OECD TG 102 / EU Method A.1; differential scanning calorimetry) ; RL1; GLP

Additional information

Besides a glass transition between -50°C (223 K) and -15°C (273 K) with an extrapolated onset of -29°C (244 K), no melting was observed below the temperature of 150°C (423 K) at which reaction and/or decomposition of the test substance started. Therefore, the test substance has no melting temperature.