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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The result was obtained from a publically available source which has been subject to peer-review and in which the original data sources are traceable.

Data source

Reference
Reference Type:
publication
Title:
EPA Pesticide fact sheet alpha Chlorohydrin
Year:
2006
Bibliographic source:
United States Environmental Protection Agency

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No details given.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
3-chloropropane-1,2-diol
EC Number:
202-492-4
EC Name:
3-chloropropane-1,2-diol
Cas Number:
96-24-2
IUPAC Name:
3-chloropropane-1,2-diol
Constituent 2
Reference substance name:
3-Chloro-1,2-propanediol
IUPAC Name:
3-Chloro-1,2-propanediol

Test animals / tissue source

Species:
rabbit

Results and discussion

In vivo

Results
Irritation parameter:
other: Unknown
Time point:
other: Unknown
Score:
> 0 - < 10
Max. score:
10

Applicant's summary and conclusion

Interpretation of results:
Category I
Remarks:
Migrated information Criteria used for interpretation of results: US EPA pesticides
Conclusions:
The substance is a severe eye irritant.