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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

boiling point
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference Type:
study report
Report date:

Materials and methods

Test guideline
according to guideline
OECD Guideline 103 (Boiling Point)
Version / remarks:
The testing laboratory is GLP compliant and the test was carried out according to the principles of GLP. An internal standard operating procedure was followed for the direct scanning calorimetry tests.
Principles of method if other than guideline:
Date 02/10/2017
SOP Reference CTL SOP 320
Test System DSC System 1
Test Filename DSC4028001957A
Crucible Type Gold-lined steel (high pressure, sealed)
Sample Preparation Tested as received
Start Temperature -40°C
Trip Temperature 400°C
Ramp Rate 4 K.min-1
Test Atmosphere Air
Sample Mass 4.7 mg
GLP compliance:
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Reference substance name:
α-Bitter acids, hop, hydrogenated, isomerized
EC Number:
EC Name:
α-Bitter acids, hop, hydrogenated, isomerized
Cas Number:
α-Bitter acids, hop, hydrogenated, isomerized
Specific details on test material used for the study:
Batch no. EXP 6. Contains 75.81% w/w potassium salt of hop tetrahydroiso-alpha acids.

Results and discussion

Boiling point
Key result
Remarks on result:
not determinable
No firm boiling point noted on DSC, as expected for a plant-derived UVCB material. Exotherm events show different components degrading, but no clear boiling point. The material decomposes before boiling.

Any other information on results incl. tables

Notes from the test report: “The sample was observed to undergo an endothermic event from -22.0°C (4.2 J.g-1). An exothermic event was then observed to commence from 125.1°C which had a heat of decomposition of -262.4 J.g-1. No further significant energetic events were noted up to 400°C.”

The DSC plot is attached – see “Illustration – picture/graph”

Applicant's summary and conclusion

Substance decomposes before boiling.