(2S)-2-amino-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoic acid

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Comparable to guideline study (EC A.10.) with acceptable restrictions

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: UN Transport Regulation Test N.1

Deviations:

no

GLP compliance:

no

Specific details on test material used for the study:

Manufactured by the Subimitter,
Batch number 78159002
Purity > 95%

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks:

Combustion Class Number (BZ = Brennzahl) 2: Catches fire briefly and estinguishes (definition according to Directive VDI 2263)

Burning time:

s

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The product has to be classified neither as highly flammable solid according to EC 440/2008, Part A, A.10., nor as readily combustible solid in class 4.1 according to the UN-Transport Regulation and nor as flammable solid according to GHS.

Executive summary:

The product has to be classified neither as highly flammable solid according to EC 440/2008, Part A, A.10., nor as readily combustible solid in class 4.1 according to the UN-Transport Regulation and nor as flammable solid according to GHS.

Reference 2

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the experience in production or handling shows that the substance does not react with water, e.g. the substance is manufactured with water or washed with water

Reference 3

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Description of key information

Flmmability:

The test item is not a flammable solid.

Flammability in Contact with Water:

The practical experience of the sponsor and the test facility shows that no gases are developed, when the test substance is in contact with water.

Pyrophoricity:

The test was not performed experimentally because practical experience exists at the sponsor and the test facility, e.g. when handling small amounts of the test substance repeatedly in air during testing. The test substance is therefore regarded as not being pyrophoric.

Key value for chemical safety assessment

Flammability:

not classified

Justification for classification or non-classification

No results were obtained to justify a classification.