N,N-dibutylformamide

Guidance on Safe Use

First-aid measures

Description of first aid measures

First aid personnel should pay attention to their own safety. If the patient is likely to become unconscious, place and transport in stable sideways position (recovery position). Immediately remove contaminated clothing.

If inhaled:

Keep patient calm, remove to fresh air, seek medical attention. Immediately administer a corticosteroid from a controlled/metered dose inhaler.

On skin contact:

Immediately wash thoroughly with plenty of water, apply sterile dressings, consult a skin specialist.

On contact with eyes:

Immediately wash affected eyes for at least 15 minutes under running water with eyelids held open, consult an eye specialist.

On ingestion:

Do not induce vomiting. Immediately rinse mouth and then drink 200-300 ml of water, seek medical attention.

4.2. Most important symptoms and effects, both acute and delayed

Symptoms: The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11., Further symptoms are possible

4.3. Indication of any immediate medical attention and special treatment needed

Treatment: Treat according to symptoms (decontamination, vital functions), no known specific antidote. Medical monitoring for at least 24 hours. Pulmonary odema prophylaxis.

Fire-fighting measures

Extinguishing media

Suitable extinguishing media:

water spray, dry powder, foam, carbon dioxide

5.2. Special hazards arising from the substance or mixture

carbon oxides, nitrogen oxides

The substances/groups of substances mentioned can be released in case of fire. Under certain conditions in case of fire other hazardous combustion products may be generated.

5.3. Advice for fire-fighters

Special protective equipment:

Wear self-contained breathing apparatus and chemical-protective clothing.

Further information:

Collect contaminated extinguishing water separately, do not allow to reach sewage or effluent systems. Dispose of fire debris and contaminated extinguishing water in accordance with official regulations.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Use personal protective clothing. Keep unprotected persons away. Ensure adequate ventilation. Avoid contact with the skin, eyes and clothing. Avoid inhalation.

Environmental precautions

Do not discharge into drains/surface waters/groundwater.

Methods and material for containment and cleaning up

For small amounts: Rinse with plenty of water. Dispose of contaminated material as prescribed.

For large amounts: Dike spillage. Pump off product.

For residues: Pick up with suitable absorbent material (e.g. sand, sawdust, general-purpose binder, kieselguhr). Dispose of absorbed material in accordance with regulations.

Cleaning operations should be carried out only while wearing breathing apparatus. Clean contaminated floors and objects thoroughly with water and detergents, observing environmental regulations. Collect waste in suitable containers, which can be labeled and sealed. Incinerate or take to a special waste disposal site in accordance with local authority regulations.

Handling and storage

Precautions for safe handling

Ensure thorough ventilation of stores and work areas. Handle in accordance with good industrial hygiene and safety practice. When using do not eat, drink or smoke. Hands and/or face should be washed before breaks and at the end of the shift.

Protection against fire and explosion:

Prevent electrostatic charge - sources of ignition should be kept well clear - fire extinguishers should be kept handy.

7.2. Conditions for safe storage, including any incompatibilities

Further information on storage conditions: Containers should be stored tightly sealed in a dry place.

Storage class according to TRGS 510 (originally VCI, Germany): (8A) Combustible corrosive substances

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Control parameters

Components with occupational exposure limits

The surveillance of the workplacControl parameters

Components with occupational exposure limits

The surveillance of the workplace by exposure measurements may be necessary, in order to proof the efficiency of safety measures, for example ventilation or the need of respiratory protection. Since this requires a specific competency, only accredited laboratories should be contracted. Regarding suitable methods to assess inhalative exposure the European Standards EN 482, 689 and 14042 are to be considered. In addition the TRGS 402 has to be observed in Germany.

64-18-6: formic acid … %

      TWA value 9 mg/m3 ; 5 ppm (OEL (EU))

indicative

      Short Term Exposure Classification:  (TRGS 900 (DE))

Category I: Substances for which the localized effect has an assigned exposure limit or for substances with a sensitizing effect in respiratory passages

      OEL 9,5 mg/m3 ; 5 ppm (TRGS 900 (DE))

Ceiling limit value/factor: 2

If the occupational exposure limit value (AGW) and the biological limit value (BGW) are complied with, there should be no risk of damage for the unborn child (see TRGS 900, Number 2.7)

PNEC

freshwater: 0,058 mg/l

marine water: 0,0058 mg/l

intermittent release: 0,58 mg/l

STP: 5 mg/l

sediment (freshwater): 15,8 mg/kg

sediment (marine water): 1,58 mg/kg

soil: 3,12 mg/kg

DNEL

worker:

Long-term exposure- systemic effects, Inhalation: 2,4 mg/m3

worker:

Long-term exposure- systemic effects, dermal: 0,7 mg/kg

Exposure controls

Personal protective equipment

Respiratory protection:

Wear respiratory protection if ventilation is inadequate. Gas filter for gases/vapours of organic compounds (boiling point >65 °C, e. g. EN 14387 Type A)

Hand protection:

Chemical resistant protective gloves (EN ISO 374-1)

Suitable materials also with prolonged, direct contact (Recommended:  Protective index 6, corresponding > 480 minutes of permeation time according to EN ISO 374-1):

butyl rubber (butyl) - 0.7 mm coating thickness

fluoroelastomer (FKM) - 0.7 mm coating thickness

Polyethylene-Laminate (PE laminate) - ca. 0.1 mm coating thickness

Manufacturer's directions for use should be observed because of great diversity of types.

Supplementary note: The specifications are based on tests, literature data and information of glove manufacturers or are derived from similar substances by analogy. Due to many conditions (e.g. temperature) it must be considered, that the practical usage of a chemical-protective glove in practice may be much shorter than the permeation time determined through testing.

Eye protection:

Tightly fitting safety goggles (cage goggles) (e.g. EN 166) and face shield.

Body protection:

Body protection must be chosen depending on activity and possible exposure, e.g. apron, protecting boots, chemical-protection suit (according to EN 14605 in case of splashes or EN ISO 13982 in case of dust).

General safety and hygiene measures

Handle in accordance with good industrial hygiene and safety practice. Wearing of closed work clothing is required additionally to the stated personal protection equipment. Avoid contact with the skin, eyes and clothing. Do not breathe vapour/spray. Wash contaminated clothing before reuse. Gloves must be inspected regularly and prior to each use.  Replace if necessary (e.g. pinhole leaks). Take off immediately all contaminated clothing. Store work clothing separately.

e by exposure measurements may be necessary, in order to proof the efficiency of safety measures, for example ventilation or the need of respiratory protection. Since this requires a specific competency, only accredited laboratories should be contracted. Regarding suitable methods to assess inhalative exposure the European Standards EN 482, 689 and 14042 are to be considered. In addition the TRGS 402 has to be observed in Germany.

64-18-6: formic acid … %

      TWA value 9 mg/m3 ; 5 ppm (OEL (EU))

indicative

      Short Term Exposure Classification:  (TRGS 900 (DE))

Category I: Substances for which the localized effect has an assigned exposure limit or for substances with a sensitizing effect in respiratory passages

      OEL 9,5 mg/m3 ; 5 ppm (TRGS 900 (DE))

Ceiling limit value/factor: 2

If the occupational exposure limit value (AGW) and the biological limit value (BGW) are complied with, there should be no risk of damage for the unborn child (see TRGS 900, Number 2.7)

PNEC

freshwater: 0,058 mg/l

marine water: 0,0058 mg/l

intermittent release: 0,58 mg/l

STP: 5 mg/l

sediment (freshwater): 15,8 mg/kg

sediment (marine water): 1,58 mg/kg

soil: 3,12 mg/kg

DNEL

worker:

Long-term exposure- systemic effects, Inhalation: 2,4 mg/m3

worker:

Long-term exposure- systemic effects, dermal: 0,7 mg/kg

Exposure controls

Personal protective equipment

Respiratory protection:

Wear respiratory protection if ventilation is inadequate. Gas filter for gases/vapours of organic compounds (boiling point >65 °C, e. g. EN 14387 Type A)

Hand protection:

Chemical resistant protective gloves (EN ISO 374-1)

Suitable materials also with prolonged, direct contact (Recommended:  Protective index 6, corresponding > 480 minutes of permeation time according to EN ISO 374-1):

butyl rubber (butyl) - 0.7 mm coating thickness

fluoroelastomer (FKM) - 0.7 mm coating thickness

Polyethylene-Laminate (PE laminate) - ca. 0.1 mm coating thickness

Manufacturer's directions for use should be observed because of great diversity of types.

Supplementary note: The specifications are based on tests, literature data and information of glove manufacturers or are derived from similar substances by analogy. Due to many conditions (e.g. temperature) it must be considered, that the practical usage of a chemical-protective glove in practice may be much shorter than the permeation time determined through testing.

Eye protection:

Tightly fitting safety goggles (cage goggles) (e.g. EN 166) and face shield.

Body protection:

Body protection must be chosen depending on activity and possible exposure, e.g. apron, protecting boots, chemical-protection suit (according to EN 14605 in case of splashes or EN ISO 13982 in case of dust).

General safety and hygiene measures

Handle in accordance with good industrial hygiene and safety practice. Wearing of closed work clothing is required additionally to the stated personal protection equipment. Avoid contact with the skin, eyes and clothing. Do not breathe vapour/spray. Wash contaminated clothing before reuse. Gloves must be inspected regularly and prior to each use.  Replace if necessary (e.g. pinhole leaks). Take off immediately all contaminated clothing. Store work clothing separately.

Stability and reactivity

Reactivity

No hazardous reactions if stored and handled as prescribed/indicated.

Chemical stability

Stable under normal conditions.

Possibility of hazardous reactions

No hazardous reactions known.

Conditions to avoid

Avoid all sources of ignition: heat, sparks, open flame. Avoid heat. Avoid pressure.

Incompatible materials

Substances to avoid:

strong oxidizing agents, strong reducing agents, acids, bases, acid chlorides

Hazardous decomposition products

Hazardous decomposition products:

irritant gases/vapours, toxic gases/vapours

Disposal considerations

Waste treatment methods

Incinerate in suitable incineration plant, observing local authority regulations.

Contaminated packaging:

Contaminated packaging should be emptied as far as possible; then it can be passed on for recycling after being thoroughly cleaned.