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Diss Factsheets

Environmental fate & pathways

Hydrolysis

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Data waiving:
study technically not feasible
Justification for data waiving:
other:

Description of key information

Determination of hydrolytic stability was not carried out using Method C.7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004 due to the test item having overall low solubility in aqueous media and being a complex mixture.

Key value for chemical safety assessment

Additional information

Determination of hydrolytic stability was not carried out using Method C.7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004 due to the test item having overall low solubility in aqueous media and being a complex mixture. The water solubility of the test item, at which all components would dissolved, was expected to be too low to perform the test as a sensitive enough analytical method was not available. Additionally, the test solution would need to be half this concentration to satisfy the test requirements. The test item, being a complex mixture, was not ideally suited to the test method. This is because components that are unstable could have significantly different hydrolytic rates, and if there are components that are stable also, this would lead to conflicting results. Additionally, hydrolysis products of complex mixtures can be the same as some of the components already present and differentiating these would not be possible. Based on the main amine, ether and phosphate ester functional groups, it was considered that the test item would not readily hydrolyse at environmentally relevant pH and temperature.