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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
other: expert assessment
Adequacy of study:
key study
Study period:
August 11, 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances

Data source

Reference
Reference Type:
other: Expert assessment
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Principles of method if other than guideline:
Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
GLP compliance:
no
Type of study:
other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances

Test material

Constituent 1
Chemical structure
Reference substance name:
1-[(2-hydroxyethyl)thio]propan-2-ol
EC Number:
229-765-0
EC Name:
1-[(2-hydroxyethyl)thio]propan-2-ol
Cas Number:
6713-03-7
Molecular formula:
C5H12O2S
IUPAC Name:
1-[(2-hydroxyethyl)sulfanyl]propan-2-ol

Results and discussion

In vivo (LLNA)

Results
Key result
Parameter:
other: skin sensitisation
Remarks on result:
other: 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation

Any other information on results incl. tables

see attached report

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.
Executive summary:

An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.