Registration Dossier
Registration Dossier
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EC number: 253-634-7 | CAS number: 37697-65-7
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
The registration substance 1-methyl-N,N',N''-tris(1-methylpropyl)silanetriamine (CAS 37697-65-7) will hydrolyse very rapidly in contact with water and atmospheric moisture (half-life <2 minutes at pH 7, 25 °C) to form methylsilanetriol (CAS 2445-53-6) and sec-butylamine (CAS 13952-84-6).
Short-term tests have been conducted with the parent substance. Fish were tested up to a maximum concentration of 100 mg/l, where turbidity of test solutions was observed throughout the test. However, no effects were observed. Also short-term toxicity to Daphnia and algal tests have been conducted with the parent substance. In these studies a design was selected to avoid overloading of the test system and to determine the maximum achievable concentration in test media considered equivalent to the occurrence of turbidity. The maximum achievable concentrations were found as <3.75 mg/l for Daphnia and <2.5 mg/l for algae in a pretest. 3.75 mg/l and 2.5 mg/l were therefore set as the highest test concentrations for Daphnia and algae, respectively. No effects on the test organisms were observed.
Classification and Labelling under Regulation (EC) No 1272/2008 (as amended) (CLP) for the registration substance is derived from the results of these tests, based on the maximum technically achievable concentration of the parent substance.
Methylsilanetriol (CAS 2445-53-6) has a predicted water solubility of 1000000 mg/l and a log Kow of -2.4 (methylsilanetriol may undergo condensation reactions in water; this obviously becomes important in the Daphnia and Algae test system and limits the concentration of test substance dissolved in water).
Sec-butylamine (13952-84-6) is miscible in water and has a log Kow of 0.74.
Conclusion on classification
The substance has short-term E(L)C50 values of >100 mg/l in fish, >3.75 mg/l in invertebrates and >2.5 mg/l in algae. It has a reliable NOEC of 2.5 mg/l in algae.
The classification is based on the maximum technicallly achievable concentration of the parent substance.
The substance hydrolyses rapidly in water. The products of hydrolysis are soluble and have low log Kow. The silanol hydrolysis product is not readily biodegradable; sec-butylamine is readily biodegradable.
These data are consistent with the following classification under Regulation (EC) No 1272/2008 (as amended) (CLP):
Acute toxicity: Not classified.
Chronic toxicity: Not classified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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