Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

In accordance with REACH Annex XI, section 2, testing is technically not feasible as a consequence of the properties of the substance (hydrolytically unstable substance and quasi-instantaneously degraded in contact with moist skin or mucous membranes to form Vanadium dioxide and hydrogen chloride).


And there are sufficient data on the breakdown products (vanadium dioxide n°CAS: 12036-21-4 and hydrogen chloride n°CAS: 9004-54-0) which were already registered in the frame of REACH. These breakdown substances are exempted to Registration following Annex V (Entry I) for this register dossier.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Link to relevant study records
short-term repeated dose toxicity: oral
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Vanadium tetrachloride is quasi-instantaneously degraded in contact with moist skin or mucuous membranes to form Vanadium dioxide and hydrogen chloride.

VCl4 + H2O => VOCl2 + 4HCl

2VOCl2 + 2H2O => 2VO2 + 4HCL

Testing Vanadium tetrachloride for long term toxicity is for this reason not relevant at all, but breakdown products have to be considered (classification for Vanadium dioxide and hydrogen

chloride have been elaborated in the frame of REACH and non classification is elaborated for long term effects).

For these reasons, no classification could be set for repeated toxicity.