Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

dissociation constant
Adequacy of study:
other information

Data source

Reference Type:
other: Body responsible for the test

Materials and methods

Test guideline
according to guideline
Principles of method if other than guideline:
Based on OECD Guidelines for Testing of Chemicals (Section 1
No 112).

The pKa was investigated spectrophotometrically using a
dilute aqueous mixed buffer solution of the test substance
S191820, ASG 10348537. The pH of the test solutions was
adjusted using potassium hydroxide and hydrochloric acid.

A UV/Visible spectrum was obtained at each pH value.

The ionic strength of the solution was maintained at a
constant level by the addition of potassium chloride

Instrument Details :

Orion EA 940 pH Meter

Perkin Elmer Lambda 900 UV Spectrophotometer

(1cm silica cells, slit width 2.0nm, data interval 1.0nm,
integration time 0.08s)

Results and discussion

Any other information on results incl. tables

pKa 1 :11.0

pKa 2 :2.0

All pKa values measured at ambient temperature 23ºC

Applicant's summary and conclusion