Registration Dossier
Registration Dossier
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EC number: 209-508-9 | CAS number: 583-55-1
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 438 (Isolated Chicken Eye Test Method for Identifying Ocular Corrosives and Severe Irritants)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-bromo-2-iodobenzene
- EC Number:
- 209-508-9
- EC Name:
- 1-bromo-2-iodobenzene
- Cas Number:
- 583-55-1
- Molecular formula:
- C6H4BrI
- IUPAC Name:
- 1-bromo-2-iodobenzene
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- other: ICE class
- Value:
- ca. 1
- Remarks on result:
- other: ICE class is I for all values of the test item.
- Other effects / acceptance of results:
- In both experiments, no significant corneal swelling, corneal opacity change or fluorescein retention change was observed during the observation period.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
- Conclusions:
- Based on the in vitro eye irritaion tests in isolated chicken eyes, the test item is not irritant to eye.
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