Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 222-824-1 | CAS number: 3623-51-6
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24-Nov-2014 to 03-Dec-2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Staatliches Gewerbeaufsichtsamt Hildeshelm
- Type of method:
- flask method
- Key result
- Water solubility:
- 0.231 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 6.3
- Conclusions:
- A water solubility value of 2.31E-01 g/L (at 20 °C, pH 6.3) was determined for the test substance according to OECD 105 (1995).
Reference
Results
Preliminary Test (non GLP)
In the preliminary test a water solubility of approx. 120 mg/L was achieved.
Main test
Water solubility results at 20 °C
Pre-incubation time |
Replicate No. |
Concentration1) (g/L) |
Mean |
24 h |
1 |
0.254 |
0.238 |
2 |
0.222 |
||
48 h |
1 |
0.213 |
0.223 |
2 |
0.233 |
||
72 h |
1 |
0.264 |
0.232 |
2 |
0.200 |
||
Mean (24 – 72 h) |
|
|
0.231 |
Deviation (%) |
|
|
6.84 |
1) Mean value of two injections, weighing factor and dilution factor of 62.5 were taken into account
Conclusions
The solubility of the test item was determined to be 0.231 g/L (pH 6.3) at 20 ± 0.5 °C.
Description of key information
Water solubility: 2.31E-01 g/L at 20 °C, pH = 6.3 (OECD 105, flask method)
Key value for chemical safety assessment
- Water solubility:
- 0.231 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
