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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

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Endpoint:
long-term toxicity to fish, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
freshwater
Duration:
30 d
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
1.001 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Neutral Organic SAR: Maximum LogKow: 8.0 (Chronic Value)
Conclusions:
Estimated Chronic Value : 1.0 mg/L
Intermediate substance is estimated to be toxic to fish with long lasting effects (Chronic toxicity).
Endpoint:
long-term toxicity to fish, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
saltwater
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
31.743 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Vinyl/Allyl Ketones: Maximum LogKow: 8.0 (Chronic Value)
Conclusions:
Estimated Chronic Value : 31 mg/L
Intermediate substance is estimated to be harmful to fish with long lasting effects (Chronic toxicity).

Description of key information

Indicated results are "Chronic values" as obtained from ECOSAR 1.11

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 mg/L

Marine water fish

Marine water fish
Effect concentration:
31 mg/L

Additional information

Lowest NOEC could be estimated to around 0.7 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is estimated to be toxic to fish with long lasting effects (Chronic toxicity).