Registration Dossier
Registration Dossier
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EC number: 276-684-1 | CAS number: 72480-09-2
Endpoint summary
Administrative data
Description of key information
Additional information
The substance is a brown powder with a characteristic odour.
In a DSC analysis showed decomposition beginning at 246 °C.
Relative density was determined by means of a pycnometer OECD 109 and the result value was D at 20 °C: 1.7353 at 20 °.
Granulometry is of considerable importance for the toxic properties of a substance as it influences aspects such as: the route of exposure of humans and toxicity by inhalation; the choice of route of administration for animal testing; the efficiency of uptake in an organism; the distribution in the environment.
The substance presented a granulometry mass median aerodynamic diameter (MMAD)= 44.5 µm. This granulometry can be considered as inhalable fractions (CEN document, EN 481‘Workplace Atmospheres - size fraction definitions for measurement of airborne particles”, 1993).
Ca 2% in volume of the test item has a particle size <= 4 µm (respirable fraction (the mass fraction of particles that reaches the alveoli).
According to Annex VII of REACH Regulation1907/2006, column 2, the study of vapour pressure does not need to be conducted for this substance but the lowest value accepted by EUSES has been reported for a complete Risk assessment (0.0000001 Pa).
Partition coefficient was determined in HPLC and was stated as 1.96 (log Pow).
The tested substance is considered very soluble, 51.48 g/L at 20.0 °C.
According to Annex VII of REACH Regulation 1907/2006, column 2 no surface activity is expected or can be predicted; therefore, the testing can be waived. As solid, the substance has no a flash point and the test can also be waived.
It is not expected to be auto-flammable, flammable, explosive and it is deemed to be potentially not oxidizing based on the chemical structure, the oxygen balance values and the known experience in the handling and use of the substance.
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