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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
14.571 µm
Percentile:
D10
Mean:
3.352 µm
St. dev.:
0.024
Percentile:
D50
Mean:
12.541 µm
St. dev.:
0.117
Percentile:
D90
Mean:
97.678 µm
St. dev.:
2.317
Conclusions:
The results of the laser diffraction test conducted to determine the particle size of V123109 are summarised in the table below. The analysis was conducted using the small using silicone oil as the dispersant.

Particle Size Analysis using small volume module (SVM) Average (μm)
Volume weighted mean 34.381
Median 12.541
Mode 8.982
MMAD (mass median aerodynamic diameter) 14.571
d10 - 10 % of material is < 3.352
d50 - 50 % of material is < 12.541
d90 - 90 % of material is < 97.678
volume of sample < 10.00 μm 41.39

Description of key information

MMAD (mass median aerodynamic diameter) 14.571 µm

Additional information