Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.025 mg/L
Assessment factor:
50
Extrapolation method:
sensitivity distribution
PNEC freshwater (intermittent releases):
0.03 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0 mg/L
Assessment factor:
50
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
20.4 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.011 mg/kg sediment dw
Assessment factor:
50
Extrapolation method:
assessment factor

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.001 mg/kg sediment dw
Assessment factor:
500
Extrapolation method:
assessment factor

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
14.8 mg/kg soil dw
Assessment factor:
10
Extrapolation method:
assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

 


 


ENVIRONMENTAL HAZARD ASSESSMENT INCLUDING DERIVATION OF PNECS


Aquatic


 


The lowest acute L(E)C50 value from the dataset was obtained in the rainbow trout (Davies & Brinkman 1998). This study was conducted on MnSO4 and the LC50 was 3.2 mg Mn/L. Note that this LC50 is quoted in terms of mg Mn/L and hence to calculate the equivalent LC50 for NaMnO4 it is necessary to make an adjustment based on the relative molecular weights of Mn compared with NaMnO4. The molecular weight of Mn is 55 and that of MnCl2 is 141.93. It is therefore necessary to multiply the LC50 measured in mg Mn/L by a factor of 2.58 to obtain the LC50 for MnCl2. Multiplying 3.2 by 2.58 = 8.26. Hence, the lowest L(E)C50 for NaMnO4 is 8.26 mg/L.


 


The lowest chronic NOEC value from the dataset was obtained in the brook trout (Davies & Brinkman 1998). This study was conducted on MnSO4and the NOEC was 0.55 mg Mn/L. This is equivalent to 1.42 mg/L of NaMnO4  when a molecular weight correction is made.


 


Sediment


 


Chronic endpoints are available for two sediment dwelling organisms, Hyalella azteca and Chironomus tentans, representing different living and feeding conditions. The lowest of these endpoints is a NOEC of 0.29 mg Mn/L, which is equivalent to 0.22 mg Mn/kg wwt sediment (assuming density of sediment of 1.3 g/cm3) and 0.57 mg Mn/kg dwt sediment (based on a conversion factor of 2.6).


 


PNEC sediment




































 


 

Value


 

Assessment factor


 

Remarks/Justification:


 

PNEC sediment
(mg Mn/kg d.w.)


 

0.0114


 

50


 

Based on the lowest endpoint (NOEC of 0.57 mg Mn/kg sediment dwt) from studies on two sediment dwelling organisms.


 

PNEC marine sediment
(mg Mn/kg d.w.)


 

0.00114


 

500


 

Based on the freshwater endpoints with an increased AF factor.


 

It should be noted that these values are considerably lower than the background concentration of manganese in European environments (452 mg/kg in sediment; “Probabilistic Distribution of Manganese in European Surface Water, Sediment and Soil and Derivation of Predicted Environmental Concentrations (PEC)”, Parametrix, 2009 and supported by GEMAS data) and hence has little relevance for assessment of any potential risk from MnSO4.


 


Terrestrial


There are a wide range of long-term toxicity endpoints available for the soil compartment, that cover three trophic levels. Therefore, the lowest NOEC is used with an AF of 10. In line with the REACH Guidance (R.10.6) the endpoints from soil studies need to be converted from experimental soil to standard soil, taking into account differences in organic matter content (equation R.10-4). Therefore, the lowest overall NOEC is actually 148 mg Mn/kg soil (i.e. NOEC of 207 mg Mn/kg soil, corrected for organic carbon content of 2.8%). 


 


PNEC soil


























 


 

Value


 

Assessment factor


 

Remarks/Justification:


 

PNEC soil (mg Mn/kg d.w.)


 

14.8


 

10


 

Based on the lowest NOEC (148 mg Mn/kg soil d.w.) from a range of long-term studies


 

It should also be noted that this value is considerably lower than the background concentration of manganese in European environments (428.6 mg/kg in soil; “Probabilistic Distribution of Manganese in European Surface Water, Sediment and Soil and Derivation of Predicted Environmental Concentrations (PEC)”, Parametrix, 2009 and supported by GEMAS data) and hence has little relevance for assessment of any potential risk from NaMnO4.


 


STP


Limited effect on sewage sludge was observed in a standard 3hr activated sludge study on MnSO4. Hence the NOEC for MnSO4is 560 mg/l (204 mg Mn/L) and the EC50is >1000 mg/L (>364 mg Mn/L). These data are used as a read-across for NaMnO4.


 


PNEC sewage treatment plant


























 


 

Value


 

Assessment factor


 

Remarks/Justification


 

PNEC stp ( mg/L)


 

20.4


 

10


 

Activated sludge respiration/inhibition test; NOEC = 204 mg Mn/L (560 mg MnSO4/L)


 

 


Assessment of PBT/vPvB Properties - Comparison with the Criteria of Annex XIII


A study by Szefer, P. and Falandysz, J. (1987) on trace metals in the soft tissues of scaup ducks provides evidence of no bioaccumulation. According to the Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT assessment, “the PBT and vPVB criteria of Annex XIII to the regulation do not apply to inorganic substances”. Therefore Mn2+ is not considered to require any further assessment of PBT properties.

Conclusion on classification

According to the 2nd ATP to the CLP Regulation (EU) No 286/2011, environmental classification of readily soluble metal compounds for which suitable ecotoxicity data is available is based upon the acute and chronic ERV.


In this case the lowest acute L(E)C50 value from the dataset was obtained in the rainbow trout (Davies & Brinkman 1998). This study was conducted on MnSO4 and the LC50 was 3.2 mg Mn/L. This is equivalent to 8.26 mg/L of NaMnO4 when a molecular weight correction is made. This is the acute ERV.


 


The lowest NOEC value from the dataset was obtained in the brook trout study (Davies & Brinkman 1998). This study was conducted on MnSO4 and the NOEC was 0.55 mg Mn/L. This is equivalent to 1.42mg/L of NaMnO4 when a molecular weight correction is made. This is the chronic ERV.


 


In cases where both the acute and chronic ERV are greater than 1 mg/L there is no need to classify for either acute or chronic effects.