Registration Dossier
Registration Dossier
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EC number: 305-897-5 | CAS number: 95193-83-2
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The in vivo toxicokinetic studies, the assessment of the physicochemical properties of the substance and the results of the toxicological studies agree on the poor absorption of the substance via oral, inhalation and dermal routes and on the minimal distribution in tissues and organs. Based on the in vivo toxicokinetic studies, it can be concluded that the substance is not significantly metabolised. The substance is quickly and almost entirely excreted with the faeces (> 90% in rats) and only a small extent (about 2% in rats) is excreted with urine.
Key value for chemical safety assessment
Additional information
A series of toxicokinetic in vivo studies on the test item reveal that the substance is mainly excreted via the faeces, as a consequence the substance is not metabolised and shows no accumulation potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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