Registration Dossier
Registration Dossier
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EC number: 241-010-7 | CAS number: 16941-12-1
Endpoint summary
Administrative data
Description of key information
Additional information
For hexachloroplatinic acid, data are read across from another platinum(IV) substance that also contains a chloro ligand, platinum(IV) chloride.
The chronic toxicity of platinum (as platinum (IV) chloride) to the soil invertebrate Enchytraeus crypticus was assessed in the publication by Havelkova et al. (2014). The study is reliable with acceptable restrictions, it is non-GLP, but follows OECD guideline 220. A laboratory test of 28 days with artificial soil was carried out to determine the effects of platinum on the reproduction of E. crypticus. Five nominal concentrations of the test item were included, alongside a negative control and a reference control. No significant effect on mortality was found. The 28-d EC50 of platinum(IV) chloride for inhibition of the reproduction of Enchytraeus crypticus was determined to be 161.9 μmol test item L-1 (93.75 μmol Pt L-1), corresponding to 54.54 mg test item L-1 (31.58 mg Pt L-1). Only an EC50 is reported in the study, but a NOEC can be determined from the data provided in the paper. The NOEC from the study is 100 µmol test item L-1 (57.91 μmol Pt L-1), corresponding to 33.69 mg test item L-1 (19.51 mg Pt L-1). The exposures used in the study were expressed only in terms of the concentration of metal in the spiking solutions.
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