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EC number: 204-371-1 | CAS number: 120-12-7
Endpoint summary
Administrative data
Description of key information
Additional information
Overview on measured bioaccumulation data in fish
The number of key publications that deserve reliability of 2 is limited: these include those of Japan CITI 1992/NITE 2002, Spacie et al. 1983, and to a certain degree those of de Voogt et al. 1991. The distribution of radiolabelled anthracene was investigated in one well-done lab-scale microcosm study that included several species and compartments (Lu et al 1978).
Reliable experimental BCF values based on valid studies with anthracene in fish range from about 1000 to about 2500.
This is largely consistent with the predicted BCF values obtained from the octanol-water partition coefficient.
Based on accepted calculations of the BCF (see EC TGD 2003, part 2, p. 126: lgBCF = 0.85*lgKow – 0.70, according to Veith et al. 1979) [also recommended in Guidance CSA (May 2008), Chapter R7C, Tab. R.7.10-3], the predicted BCF would be ~1900. Using the other published and commonly used lgKow of 4.54 (Karickhoff et al. 1979; WHO-EHC 202 1998), then a predicted BCF of 1440 results.
The Guidance CSA (May 2008), Chapter R7C, Tab. R.7.10-4 relates the logKow range from 4.5 to <5 with a BCF range in fish from 2000 to 5000. It is obvious that the BCF values of anthracene based on the logKow values are expected at the low end of this range, indicating B.
Species |
BCF |
Test system |
Type |
Val. |
References |
Fish |
|||||
Cyprinus carpio |
1660-2820 |
OECD 305 (15 µg/L) |
Equi (parent) |
2 |
CITI 1992 |
Cyprinus carpio |
903-2710 |
OECD 305 (1.5 µg/L) |
Equi (parent) |
2 |
CITI 1992 |
Gambusia affinis |
1029 |
lab-scale microcosm |
Equi (parent), |
2 |
Lu et al. 1978 |
L. macrochirus |
900 |
S |
k1/k2(total) |
2 |
Spacie et al. 1983 |
L. macrochirus |
675 |
S |
k1/k2(corrected) |
2? |
Spacie et al. 1983 |
P. reticulata |
3900 |
S |
Equi (parent) |
2 |
De Voogt et al. 1991a |
P. reticulata |
7260 |
S |
k1/k2(parent) |
3 |
De Voogt et al. 1991b |
P. reticulata |
4550 |
R |
Equi (parent) |
3 |
De Voogt et al. 1991c |
P. promelas |
6760 |
S |
k1/k2(parent) |
3 |
De Maagd et al., 1996 |
Carassius auratus |
162 |
S, initial conc. >> water solubility |
k1/k2(parent) |
3 |
Ogata et al. 1984 |
L. melanotus |
910 |
S |
k1/k2(unclear) |
3 |
Freitag et al. 1985 |
S = static; R = renewal of test medium; equi = equilibrium method (steady state);
k1/k2 = kinetic method by determining uptake rate (k1) and elimination rate (k2)
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