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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.

Data source

Reference
Reference Type:
study report
Title:
Unnamed

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)ethan-1-one
Cas Number:
620176-90-1
Molecular formula:
C11H11FO2
IUPAC Name:
1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)ethan-1-one
Test material form:
liquid
Details on test material:
- Name of test material (as cited in study reports): JNJ-7928531-AAA (T001481)
- Physical state: liquid
- Appearance: Colourless, light yellow to brown liquid

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
> 500 g/L
Medium:
ethanol
Solubility:
> 500 g/L
Medium:
isopropanol
Solubility:
> 500 g/L
Medium:
other: dichloromethane
Solubility:
> 500 g/L
Medium:
other: 2-propanone
Solubility:
> 500 g/L
Medium:
dimethylformamide
Solubility:
> 500 g/L
Details on results:
no data

Applicant's summary and conclusion

Conclusions:
The solubility of T001481 in various organic solvents was determined to be > 500.0 g/L