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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

The substance is readily biodegradable, as observed in a readily biodegradability test according to OECD TG 301B.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

The biodegradation potential of the substance in water was determined in a screening study according to OECD TG 301B (CO2 -Evolution Test) and in compliance with GLP criteria (Charles River, 2017). In this study, 41.5 mg/L test item (corresponding to 12 mg TOC/L) was inoculated with activated sludge from predominantly domestic sewage for 28 days under aerobic conditions in the dark. During the incubation period degradation was followed by determining the carbon dioxide produced. In addition, biodegradation of the reference substance sodium acetate (positive control) and inhibitory effects (toxicity control) were determined. Biodegradation of the reference substance was 85% after 14 days. Biodegradation degree of the toxicity control was 80% after 14 days. After the 28-day incubation period 82% of the test substance was biodegraded. The pass level of 60% degradation was reached within 11 days after the start of the test. Further calculation with mean values of biodegradation indicate the 10-day window was met. Based on these findings, the test substance is classified as readily biodegradable.