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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30.12.2003 - 05.03.2004
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
Adopted July 27, 1995
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-bromo-4'-chloro-2'-(o-fluorobenzoyl)acetanilide
EC Number:
216-437-7
EC Name:
2-bromo-4'-chloro-2'-(o-fluorobenzoyl)acetanilide
Cas Number:
1584-62-9
Molecular formula:
C15H10BrClFNO2
IUPAC Name:
2-bromo-4'-chloro-2'-(o-fluorobenzoyl)acetanilide
Test material form:
solid: particulate/powder

Results and discussion

Water solubilityopen allclose all
Water solubility:
0.999 mg/L
Temp.:
20.5 °C
pH:
3.6
Remarks on result:
other: flow rate 24.4 ml/h
Remarks:
column 1
Water solubility:
0.983 mg/L
Temp.:
20.5 °C
pH:
6.8
Remarks on result:
other: flow rate 12.5 ml/h
Remarks:
column 1
Water solubility:
0.993 mg/L
Temp.:
20.5 °C
pH:
4.1
Remarks on result:
other: flow rate 24 ml/h
Remarks:
column 2
Water solubility:
0.965 mg/L
Temp.:
20.5 °C
pH:
6.9
Remarks on result:
other: flow rate 11.8 ml/h
Remarks:
column 2

Applicant's summary and conclusion

Conclusions:
The water solubility of BFB at 20.5 ± 0.4°C is 0.99 mg/l, using the column elution method.