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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Physical & Chemical properties

Partition coefficient

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Description of key information

- Measurement of the partition coefficient is technically not feasible because the substance is hydrolytically instable. Instead a QSAR calculation was performed using Estimation Programs Interface Suite™ for Microsoft® Windows v4.11. The prediction revealed a logKow of 0.81 for glycolide.

- The partition coefficient of glycolic acid, the break down product of hydrolytically instable glycolide, was determined to be < 0.3 according to the available information of Collander, R. (1951)

(Collander, Runar. "The partition of organic compounds between higher alcohols and water."Acta chem. scand 5.12959 (1951): 774-780.)

Key value for chemical safety assessment

Additional information

The substance glycolide is hydrolytically instable and decomposes to glycolic acid, thus experimental determination of the partition coefficient is not possible. In order to predict the logKow of glycolide a QSAR estimation was performed. Furthermore, there are data from published studies.