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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 Jan 2000 - 14 Jan 2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: done under OECD method and GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EC Directive 92/69/EEC, Part C, Method C3
GLP compliance:
yes

Test material

Constituent 1

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: Direct addition of test substance to diluent water with
ulrasonication to aid dispersion.

Test organisms

Test organisms (species):
other: Selanastrum capricornatum

Study design

Limit test:
no
Total exposure duration:
72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
32 mg/L
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.99 mg/L
Basis for effect:
growth rate

Applicant's summary and conclusion

Conclusions:
BMS 217947-01 inhibited the growth of Selenastrum Capricornutum , Strain No. CCAP 278/4 at concentrations tested in excess of 0.99mg/l under the conditions of this test. The EbC50 (72 hours) was 9.7mg/l and the ErC50 (0-72 hours) was 32mg/l
Executive summary:

BMS 217947-01 inhibited the growth of Selenastrum Capricornutum , Strain No. CCAP 278/4 at concentrations tested in excess of 0.99mg/l under the conditions of this test. The EbC50 (72 hours) was 9.7mg/l and the ErC50 (0-72 hours) was 32mg/l